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BioVaxys (CSE:BIOV) files patent for pan-sarbecovirus vaccine

Health Care
CSE:BIOV
20 October 2021 11:15 (EDT)

BioVaxys Technology (BIOV) has filed a provisional patent application for its viral antigen vaccine platform.

The vaccine is designed to elicit a broad cross-reactive immune response against most or all sarbecoviruses, the family of coronaviruses that include the virus which causes Covid-19.

A recent study evaluated those who had a natural immunity to SARS-CoV-1, which first broke out in 2003, and who had received immunization against SARS-CoV-2. The study revealed that those individuals had antibodies to eight other sarbecoviruses in addition to SARS-CoV-1 and SARS-CoV-2.

This cross-reactivity was due to similarities in the S-spike protein. Sarbecoviruses such as SARS-CoV-1 and SARS-CoV-2 all bind to the ACE2 receptor, which makes them highly transmissible.

BioVaxys plans to use its vaccine platform to immunize those who have recovered from Covid-19 or who are fully vaccinated against the virus with a WHO-recognized vaccine.

Dr. David Berd, Chief Medical Officer of BioVaxys, commented,

“Scientists dream of a pan-Coronavirus vaccine that would protect the population against any SARS-like respiratory virus that might mutate and emerge from a wild animal in the future.

“Our approach,” he added, “could constitute a pan-sarbecovirus vaccine that would protect humans against a very dangerous subgroup of Coronavirus that could emerge from the wild and cause as much devastation as Covid-19.”

The company’s novel vaccine is composed of dinitrophenyl (DNP)-modified S-spike protein of SARS-CoV-1. At this time, BioVaxys is not claiming that its vaccine platform has the ability to treat the SARS-CoV-2 virus.

James Passin, CEO of BioVaxys, commented that there are almost 4 billion people who could benefit from this vaccine, once it is developed.

“This total target population,” he said, “represents a massive commercial opportunity for proposed our pan-sarbecovirus booster vaccine, which has the potential to confer cross-reactive neutralizing antibodies, not only against all Covid-19 variants, but future emerging dangerous zoonotic sarbecoviruses.”

BioVaxys Technology is a clinical-stage biotechnology company that is developing viral and oncology vaccine platforms, as well as immuno-diagnostics.

BioVaxys Technology Corp. (BIOV) is currently up 15.71 per cent, trading at $0.405 per share as of 10:45 am ET.

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